Coenzyme Q10 (also known as ubiqinone) is a vitamin-like substance which plays a vital role in the body's energy supply mechanism, acting in conjunction with enzymes (hence the name coenzyme Q10) to convert sugars and fat into energy. Coenzyme Q10 is also important as an antioxidant within the body. Coenzyme quinones occur in several chemical forms, with coenzyme Q10 being the only form found in human tissues. The human body is able to synthesize (in the liver) a limited amount of coenzyme Q10, with the remainder being obtained from the diet.
Rich sources of coenzyme Q10 include fish (mackerel, salmon, sardines) and nuts. Under normal circumstances, the body is able to maintain adequate levels of coenzyme Q10. However, coenzyme Q10 levels decrease with age, and are depleted by intense physical exercise or illness. Coenzyme Q10 levels are also depleted in patients prescribed cholesterol-lowering statin drugs.
Coenzyme Q10 is an essential cofactor of enzymes involved in the energy production process. Coenzyme Q10 is stored in mitochondria, structures found within cells responsible for the generation of energy (in the form of a molecule called ATP). Tissues with a high-energy requirement (heart, liver, skeletal muscles) contain higher numbers of mitochondria within their cells. Coenzyme Q10 is also important within the body as a major fat-soluble antioxidant, protecting cell membranes from the damaging effects of free radicals, in a complementary manner to vitamin E. Coenzyme Q10 promotes healthy cardiovascular function, and healthy immune function (cells involved in immune response have a high energy dependence). Mitochondria illustration: Inside the mitochondria, energy is produced from nutrients in the food we eat. A Q10 deficiency may be one of the reasons why cells fail to produce energy. This, in turn, weakens the body’s ability to protect itself against illness and the onset of old age.
The generally recommended intake for coenzyme Q10 is 30 to 200mg/day, taken with meals, to enhance absorption.
Coenzyme Q10 is generally well tolerated, with no serious adverse effects reported in long-term use. Very rarely, individuals may experience gastrointestinal disturbance. There are no known toxic effects, and coenzyme Q10 cannot be overdosed. Coenzyme Q10 is not recommended for pregnant or lactating women, in whom the effects of coenzyme Q10 have not been extensively studied. No significant interference of coenzyme Q10 with other drugs has been reported.
Each capsule of Pharma-Nord Bio-Quinone Q10 contains coenzyme Q10 in a highly absorbable form, using a patented oil based delivery system.
Pharma-Nord Bio-Quinone is manufactured under Danish pharmaceutical control, and is available in capsules containing 10mg, 30mg, 100mg and 200mg of coenzyme Q10 respectively. The intake of Bio-Quinone Q10 recommended by Pharma-Nord is 30 to 200mg/day.